Does Attenuated Mckittrick-Wheelock Syndrome Exists?

McKittrick-Wheelock Syndrome (Electrolyte Depletion Syndrome)

McKittrick-Wheelock syndrome: a rare cause of diarrhoea.

McKittrick-Wheelock syndrome is a rare disorder caused by fluid and electrolyte hypersecretion from a rectal tumour. The most frequently reported tumours are villous adenomas. Dehydration with severe hyponatremia, hypokalemia, metabolic acidosis, acute renal failure and watery diarrhoea is typical. The authors present a case of McKittrick-Wheelock syndrome caused by rectal adenocarcinoma.

McKittrick-Wheelock syndrome - Prolapsed giant villous adenoma of the rectum.

Degenerate hypersecretory villous adenoma of the rectum is an uncommon, life-threatening condition. Its diagnosis is clinically challenging since cardinal symptoms are neurological and metabolic in nature because of significant fluid and electrolyte disorders induced by severe diarrhea. Even though the condition was first described back in 1954 its pathophysiology remains unknown. Management is...

The McKittrick–Wheelock syndrome: a rare cause of curable diabetes

UNLABELLED McKittrick-Wheelock syndrome (MWS) is a rare consequence of severe dehydration and electrolyte depletion due to mucinous diarrhoea secondary to a rectosigmoid villous adenoma. Reported cases of MWS commonly describe hypersecretion of mucinous diarrhoea in association with dehydration, hypokalaemia, hyponatraemia, hypochloraemia and pre-renal azotemia. Hyperglycaemia and diabetes are ...

McKittrick–Wheelock syndrome presenting with dermatomyositis and rectal prolapsed

McKittrick-Wheelock syndrome is a rare disease characterized by a large hypersecretory rectosigmoid villous adenoma resulting in persistent large volume diarrhea, electrolyte abnormalities, and renal dysfunction. We report an unusual presentation of this syndrome in a patient who developed persistent diarrhea along with dermatomyositis and rectal prolapse and was later discovered to have a larg...